Resident Evil Requiem – Grace Care Center Walkthrough

Resident Evil Requiem features two protagonists whose experiences alternate throughout the story. After the events of Wrenwood Hotel, you start with Grace in the Rhodes Hill Chronic Care Center, and the objective for the walkthrough is straightforward but challenging: collect all three Quartz pieces and insert them into the Central Hall door to unlock the way to the Courtyard.

1. Unlock the Cherub Marked Door

Collecting progress notes

After the introductory cutscene, you regain control of Grace Ashcroft inside the facility. You will need to restore power to explore more areas in the facility, as there’s no light. 

1. Immediately inspect the Progress Notes on the table to add them to your inventory.
2. Proceed down the main hallway and continue straight until you reach a gated door.
3. Near this gate, you’ll find two fuse slots required to open the path forward.
4. Search nearby tables to obtain the Cherub Key.
5. Use the Cherub Key on the Cherub-marked door to unlock the next room.

Cherub key

Save Game in Cherub Room

saving game

After unlocking the Cherub door, exit the room and turn right down the corridor. You’ll reach a red-lit area with a wall switch. Activate it to restore power and visibility. Room 201 functions as a Safe Room, containing a typewriter/save point.

2. Get the Screwdriver and First Fuse

Prep room

Once you’ve secured your first Safe Room inside the Care Centre, the next major objective is to gather the essential tools that will unlock deeper areas of the facility. These tools — the Screwdriver and the Fuse — not only grant access to previously blocked zones but also introduce a key environmental hazard: the spectral stalker known as The Girl.

How to Get the Screwdriver

1. Exit the Safe Room and move back into the main corridor. Make sure the lights remain on as you walk toward the right-hand hallway that leads to the Prep Room. 
2. Step inside the Prep Room and locate the movable cart near the shelving or boxes. Push the cart forward and climb onto it to reach the upper area of the room. This elevated section gives you access to the toolbox positioned on the upper-right side.
3. Open the toolbox and take the Screwdriver. Be cautious — if the lights in the Prep Room are off, The Girl can spawn and begin chasing you. Always keep the room illuminated when collecting tools.
4. With the Screwdriver in your inventory, leave the Prep Room and proceed toward the Reception area. There, a small panel or compartment will require the Screwdriver to open. Interact with it to retrieve the Fuse, which powers the main doors further into the Care Centre.
5. Return to the previously locked door near the start of the hallway. Insert the Fuse into the receptacle next to the door. Once the Fuse is in place, the system powers up, the lights turn on, and the door opens automatically, granting access to new areas of the Care Centre.

lighter

3. Explore the West Wing & Avoid Enemies

Inserting fuse

The West Wing introduces more dynamic navigation and the presence of powerful enemies that actively pursue you.

1. After installing the Fuse, proceed through the newly opened door toward the West Wing entry.
2. Use the West Wing Keycard (found earlier or nearby) to unlock the door.
3. Enter the kitchen area; listen carefully for audio cues like heavy footsteps — these often signal enemy approach.
4. If the Chef enemy appears, don’t engage directly. Instead, locate a metal cart with a large pot.
5. Push the cart to clear the path or create obstacles between you and the chef.
6. If he vocalizes “Wrong or next”, use this as a cue to back away to a safer area until he stops pursuing.
7. Once past him, follow the kitchen exits into a larger hallway zone.
8. Continue moving through this wing to locate side rooms, item caches, and a shortcut that leads back toward the West Wing entrance.

West Wing

4. Collect the Moon Quartz

S&S M232 Pistol

The first of the three Quartz cubes, the Moon Quartz, is obtained by solving a puzzle box in the Chairman’s Office. This Quartz is required for later progression and unlocks further areas of the Care Center.

1. Follow the West Wing hallway past the kitchen into a broader lounge area.
2. Look for the Chairman’s Office — often adjacent to dining sections and side corridors.
3. Inside the Chairman’s Office, search for a desk with a Pencil you can pick up.
4. Leave the office briefly and locate a blank notepad nearby.
5. Collect the S&S M232 from the pistol behind the Bar.
6. Use the Pencil on the notepad — this causes Grace to rub graphite over the page, revealing the hidden puzzle pattern.
7. Return to the Puzzle Box in the Chairman’s Office.
8. Input the correct sequence based on your shaded clues: Moon → Sun → Star → Moon
9. The puzzle box opens, granting you the Moon Quartz.
10. Store it in your inventory or in a nearby storage box if inventory space is tight.

Puzzle Box

Find the Lead Researcher’s Office

Red Jewel

The Lead Researcher’s Office is a key area in the Care Centre where Grace can collect essential items like the East Wing Keycard, the Hemolytic Injector, and gain access to the Blood Lab to obtain the Blood Collector and Blood Specimen.

1. Exit the Chairman’s Office and move to the right to return to the Central Hallway while keeping an eye out for the patrolling Chef enemy.
2. Head toward the back of the hallway and insert the Moon Quartz into the locked door to open access to the next corridor.
3. Proceed into the Parlor and use the Red Jewel to unlock the door while avoiding detection by the Chef.
4. Inside the Parlor, collect the Antique Coins to use for upgrades before continuing deeper into the Care Centre.
5. Move through the Examination Room to reach the East Wing Lobby, making sure to pick up the Hemolytic Injector to protect yourself from zombies along the way.
6. At the end of the hallway, enter the Blood Lab and retrieve the Blood Collector and Blood Specimen, enabling crafting with Infected Blood for future objectives.
7. Continue along the corridor until you reach the staircase, then ascend to enter the Lead Researcher’s Office

Lead Researcher’s Office

5. Collect the Sun Quartz

Killing Zombies

In the East Wing of the Care Centre, you will encounter Chunk, a patrolling enemy who adds a new layer of threat to navigation. Before facing him, you must thoroughly explore and collect important items such as the ID Wristband and the Sun Quartz, which are required to unlock further areas and solve puzzles in the facility.

1. Enter the Lead Researcher’s Office and explore the room thoroughly to examine all pictures and objects for puzzle clues.
2. Locate the Sun Quartz puzzle box, which is secured with a padlock, and note that it requires the Corrosive from the Conference Room to unlock.
3. Interact with all the pictures in the room to gain additional hints for solving the puzzle.
4. Leave the Lead Researcher’s Office and walk down the hallway to pick up the ID Wristband, making sure you have enough inventory space to carry it.
5. Pass through the Examination Room and take the door on the left to reach the staircase.
6. Climb the stairs to enter the waiting room and continue into the East Wing Lobby, where you encounter Chunk patrolling the area for the first time.
7. Observe his movement carefully and plan your route to avoid detection while continuing to collect items needed for the Sun Quartz puzzle.

East Wing Lobby location

Insert the Sun Quartz into the Door

Hemolytic Injector

After collecting the Sun Quartz, your next objective is to unlock the door in the East Wing.

1. Collect the Sun Quartz from the puzzle box and return carefully through the East Wing while avoiding Chunk, who patrols the hallway and can chase you quickly.
2. Use the Hemolytic Injectors and available bullets if Chunk engages, but prioritize stealth to conserve resources.
3. Proceed to the Conference Room and use the Sun Quartz to unlock the door and gain access to the next area.
4. Be aware of another enemy guarding the path and move carefully to pick up the Corrosive at the end of the corridor without being noticed.
5. Return to the Lead Researcher’s Office and input the puzzle code Star → Sun → Moon → Sun on the Sun Quartz box.
6. Retrieve the Sun Quartz and the Leatherbound Notebook from the box.
7. Finally, go back to the Guard Office and insert the Sun Quartz into the door to open the next section of the Care Centre and continue progression.

Stealth combat

6. Find the Artificial Organs

Combat

Once you have the Level 1 ID Wristband, your next objective is to locate the Artificial Heart and Artificial Lungs to progress further in the Care Centre. These organs are required to complete the organ puzzle in the Examination Room and unlock the Level 2 ID Wristband

1. Use your Level 1 ID Wristband to enter the Garage in the West Wing of the Care Centre and locate the Organ Transport Box at the back of a van.
2. Retrieve the Wrench from the Custodian’s Office, which is located near the Garage, to help unlock the Cold Storage door.
3. Return to the Garage, manage your inventory, and interact with the Organ Transport Box. If the van driver interferes, shoot him to clear the path.
4. Use the instructions from the Leatherbound Notebook to solve the puzzle on the Organ Transport Box and acquire the Artificial Lungs.
5. Take the stairs to reach the Cold Storage door and use the Wrench to unlock it.
6. Inside Cold Storage, collect the Artificial Heart and carry it back to the Examination Room, the same location where you previously found the corpse without organs.
7. Interact with the corpse to insert both the Artificial Heart and Lungs.

Completing this puzzle causes the corpse to collapse and rewards you with the Level 2 ID Wristband, granting access to new areas in the Care Centre and enabling further progression.

Organ Transport Box Puzzle

Cold Storage

Make sure you have the Organ Transport Box in your inventory, which you picked up from the back of the open van in the Garage after using a Level 1 ID Wristband to unlock that area.

1. Open your inventory and select the Organ Transport Box, then examine it to bring it up on screen.
2. Rotate the box around until you see the back panel; this exposes the puzzle interface you need to interact with.
3. Press/interact with the large dial to change the setting from “Auto” to “Hand.” This switches the mechanism into manual mode.
4. Slide the right‑hand slider to the middle position. This positions it part‑way up the panel and is required for the correct configuration.
5. Flip the numbered switches into their correct positions: Switch 1: Up, Switch 2: Down, Switch 3: Up, Switch 4: Up, Switch 5: Down
6. Once all switches and the slider are in place, return the dial from “Hand” back to “Auto.” This final step triggers the mechanism and pops the box open.
7. Inside the Organ Transport Box, you will find the Artificial Lungs. Pick them up — they are required for the organ transplant puzzle in the Examination Room.

7. Collect the Star Quartz

Emily

After completing the organ puzzle and obtaining the Level 2 ID Wristband, your next objective is to locate the Star Quartz, the final Quartz cube required to unlock the Central Hall Courtyard.

1. Use your Level 2 ID Wristband to enter the Isolation Ward of the Care Centre and make your way to the Security Manager’s Office.
2. Inside the Security Manager’s Office, locate the puzzle box that contains the Star Quartz.
3. Observe that the puzzle box uses buttons, but the symbols are worn off and cannot be read directly.
4. Bring Emily from the Medication Room to the puzzle box so she can read the Braille and solve the puzzle on your behalf.
5. Once Emily completes the puzzle, collect the Star Quartz from the box.
6. Be aware that Emily is kidnapped as part of the story sequence and taken to the Basement, but after completing the Basement section, you recover the Star Quartz.
7. Return to the Central Hall door in the Care Centre and insert the Moon, Sun, and Star Quartz into their respective slots.

Star Quartz

This action unlocks the door to the Courtyard, allowing you to progress to the next area and continue the Care Centre chapter.

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