Throughout Resident Evil Requiem, you’ll encounter a series of locked safes hidden in key areas like the Rhodes Hill Care Centre and the ARK research facility. These safes are optional, but cracking them rewards you with valuable items, including Antique Coins, ammo, healing supplies, maps, and crafting materials.
Opening every safe also contributes toward the “No Safe Is Safe” achievement or trophy, encouraging thorough exploration as you progress through the game’s narrative.
1. All Safe Locations, Codes & Rewards
Unlike ambient chests or simple lockers, these safes require a unique three‑number combination entered via a rotating dial, and each one holds valuable loot — from Antique Coins that can be spent on upgrades to ammunition, healing items, crafting materials, and even rare collectibles like the Raccoon Roundup Map.
| Safe Location | Where It Is | Normal/Standard Code | Insanity Mode Code | Rewards |
|---|---|---|---|---|
| Bar & Lounge Safe | Care Centre (West Wing), behind the bar counter | Left 10 → Right 80 → Left 30 | Right 20 → Left 50 → Right 30 | 3 × Antique Coins |
| Examination Room Safe | Care Centre (East Wing), inside the Examination Room cabinet | Right 30 → Left 10 → Right 50 | Left 50 → Right 30 → Left 90 | 3 × Antique Coins |
| Waiting Room Safe | Care Centre Waiting Room, behind the reception desk | Pre‑open / no code | Pre‑open / no code | 2 × Antique Coins |
| Basement Furnace Safe | Care Centre Basement, near furnace side room | Right 60 → Left 40 → Right 80 | Left 70 → Right 50 → Left 20 | Handgun Ammo + Mr. Raccoon Map |
| ARK Sterilization Chamber Safe | ARK Facility, Sterilization Chamber (northeast corner) | Right 10 → Left 90 → Right 20 | Left 80 → Right 50 → Left 0 | 15 × Handgun Ammo + Molotov + Med Injector |
| ARK Monitor Control Room Safe | ARK Facility, Monitor Control Room near lobby | Left 50 → Right 60 → Left 80 | Right 20 → Left 0 → Right 70 | Med Injector + Acid Bottle + Empty Bottle |
2. Tips For Getting Safe Codes
- Safes have their codes written in nearby notes or files, so exploring thoroughly before using codes can be rewarding.
- Opening all safes contributes to the No Safe is Safe achievement/trophy.
- Antique Coins help unlock upgrades such as Hip Pouches (increasing inventory) and weapon mods, while ammo and healing items make difficult fights easier.
- Some safes appear only after special conditions — for example, the Basement Furnace Safe only becomes accessible once you reach the basement and power the furnace.










